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GLYCEROSOMES ®

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Glycerosomes are specialized phospholipid-based vesicular systems enriched with up to 50% glycerol. Their unique composition enhances vesicle deformability and stability, enabling efficient transdermal delivery of hydrating and skin-soothing agents. The combined action of lipid fusion with the stratum corneum and glycerol’s strong humectant properties promotes superior skin penetration, moisture retention, and therapeutic efficacy.  

GLYCEROSOMES ®

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FEATURES AND KIENTICS

Superior absorption, targeted delivery, and sustained action

Glycerosomes® are phospholipid vesicles enriched with glycerin that hydrate, repair the barrier, and enhance active delivery. They fuse with skin lipids to improve penetration, retain moisture to reduce TEWL, and provide 5× higher flux with sustained release up to 8 hours.

Phospholipid bilayer enriched with ≤50% glycerin
Enhances lipid fusion with skin barrier
Strong stratum corneum & epidermal retention
Improves hydration, elasticity & barrier repair
5× higher transdermal flux vs. liposomes
Sustained release up to 8 h.
Product Features

Mechanism of Action

1
Enhanced skin fusion & delivery – Phospholipid vesicles (20–150 nm, Z-potential −30 to −50 mV) merge with skin lipids, driving deeper penetration and improving localized drug retention 5× over liposomes.
2
Moisture retention & barrier repair – Up to 50% glycerin locks water in the stratum corneum, softens the barrier, reduces TEWL, and boosts elasticity.
3
Sustained release & superior flux – Provides fast permeation with prolonged release for up to 8 hours, ensuring longer-lasting hydration and active delivery.
Mechanism illustrative image
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