Liposomal Tri-Active System is an advanced nanotechnology-based delivery platform that encapsulates three bioactive compounds: salicylic acid (SA), glycolic acid (GA), and lauric acid (LA) within liposomes. This system leverages the synergistic effects of these agents to address key pathogenic factors of acne including follicular hyperkeratinization, microbial proliferation, and inflammation. Encapsulation within liposomes enhances skin penetration, provides controlled release, and reduces the potential for irritation, thereby improving both efficacy and tolerability.