Technology Behind
LipoKaff® HANCER is an advanced transferosome-based delivery system engineered for targeted skin and scalp applications. It enhances the stability and dermal bioavailability of caffeine in cosmetic formulations through optimized molecular architecture. Upon application, it forms a hydrating film that adheres to the skin, ensuring prolonged release and deeper penetration.
In skincare, LipoKaff® HANCER supports skin hydration, caffeine stability, and targeted delivery to the dermis, enhancing overall efficacy. In hair care, it promotes scalp microcirculation, reduces hair loss, and stimulates stronger hair growth. These multifunctional benefits are enabled through precise nano-vesicle design and skin-mimetic penetration properties.
Mechanism of Action
Caffeine plays a multifunctional role in skin and hair care through several well-documented mechanisms. It helps defend skin cells from UV-induced damage by exerting strong antioxidant activity, thereby reducing the effects of photoaging. In addition, it enhances microcirculation within the skin, which revitalizes tissue and contributes to a healthier, more even skin tone.
Caffeine also inhibits the 5-reductase enzyme, supporting hair follicle health and promoting hair growth. Furthermore, it stimulates lipolysis, helping to prevent fat accumulation in adipose cells, making it particularly effective in anti-cellulite formulations.
Optimized Stability & Delivery
Advanced vesicle design enhances caffeine stability and ensures effective, sustained penetration into deeper skin layers.
Skin Hydration & Protection
Forms a protective film on the skin surface that locks in moisture, improving hydration and barrier function.
Hair & Scalp Revitalization
Stimulates scalp circulation, helping prevent hair loss while promoting stronger, healthier hair growth.
Pharmacokinetics
Skin Penetration Performance
LipoKaff® HANCER utilizes advanced transferosomal technology to significantly enhance the transdermal delivery of caffeine.
The LipoKaff® HANCER formulation achieved approximately 4-fold higher penetration into the receptor phase compared to free caffeine (Caf).
Compared to conventional liposomes, it demonstrated around 3-fold greater skin permeation, indicating superior delivery efficiency.
No chart data available for this technology.
